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Los Osos Vacation Rentals and Hotels

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We have over 200 properties in the Los Osos, California area.
Please browse our top 30 properties below


Hotels in the Los Osos/San Luis Obispo area.

	Sycamore Mineral Springs Resort				From $139.00/nt 3 Star Hotel
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Surround yourself with the natural beauty and charming serenity of Sycamore Mineral Springs Resort. A natural Hot Springs resort since 1897, we offer the


	Madonna Inn San Luis Obispo				From $180.00/nt 3 Star Hotel
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A landmark on CaliforniaÃ?Â¢??s Central Coast for over forty-five years. The world-renowned Madonna Inn offers 108 rooms, uniquely decorated with a special


	Courtyard by Marriott San Luis Obispo				From $139.00/nt 3 Star Hotel
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The Courtyard by Marriott is San Luis Obispo's newest hotel and is conveniently located near Cal Poly and is 7 mi to Pismo and Avila Beach. The Courtyard


	San Luis Obispo San Luis Creek Lodge				From $165.33/nt
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Brand new luxury inn, ideally located in uptown San Luis Obispo in a quiet streamside setting. 100 percent non-smoking. Children 2 years and older charged


	Rose Garden Inn San Luis Obispo				From $60.00/nt 2 Star Hotel
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Cruise the 101 to the college town of San Luis Obispo on California's central coast. The Rose Garden Inn of San Luis is the perfect stop for your next


	Travelodge San Luis Obispo				From $48.45/nt 2 Star Hotel
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The San Luis Obispo Travelodge, a AAA two diamond hotel, is located in Central California Wine Country, home to over 50 vineyards and a short six blocks


	San Luis Obispo Ramada Inn Olive Tree				From $60.00/nt 2 Star Hotel
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Ramada San Luis Opisbo is located in the heart of the Central Coast and just minutes from California Poly San Luis Opisbo, we are conveniently located


	Travelodge Downtown San Luis Obispo				From $32.00/nt 1 Star Hotel
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Nestled in the California mountains the San Luis Obispo Downtown Travelodge is located within walking distance of the beautiful and historic downtown San


	Days Inn San Luis Obispo				From $89.53/nt 2 Star Hotel
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The Days Inn San Luis Obispo is just one mile from the shops and weekly market of Higara.Pet friendly rooms avail. upon request


	Comfort Inn & Suites Lamplighter				From $79.99/nt 3 Star Hotel
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The Comfort Inn and Suites Lamplighter is located in the heart of San Luis Obispo. Just minutes away from historic downtown where you will find The Mission,


	San Luis Obispo Best Western Somerset Inn				From $89.00/nt 3 Star Hotel
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Enjoy convenient access to Cal Poly University and beautiful Pacific Coast beaches while staying at this San Luis Obispo, California hotel. Welcome to


	San Luis Obispo Apple Farm				From $138.67/nt 3 Star Hotel
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Traditional American hospitality, comfortable lodging, fresh food and honest value are the guiding principles behind the popular Apple Farm Inn. The Apple


	Best Western Royal Oak Hotel				From $88.00/nt 3 Star Hotel
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Enjoy everything San Luis Obispo has to offer during your stay at the Best Western Royal Oak Hotel. For those searching for sand and surf, our beaches


	Holiday Inn Express San Luis Obispo Ca				From $105.00/nt 3 Star Hotel
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Great Value-For-Money At This Limited-Service Hotel. 2 Miles from Beautiful Pismo Beach and 2 Miles from Downtown Grover Beach. Swimming Pool (Seasonal)


	Quality Suites San Luis Obispo				From $126.93/nt 3 Star Hotel
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Quality Suites San Luis Obispo is located a half mile from Cal Poly University and less than one mile form Mission San Luis Obispo and downtown San Luis


	Vagabond Inn San Luis Obispo				From $60.00/nt 2 Star Hotel
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Vagabond Inn San Luis Obispo is located just off the 101 Freeway in San Luis Obispo, walking distance from the famed Madonna Inn and shopping. We are near


	Embassy Suites Hotel San Luis Obispo				From $109.00/nt 3 Star Hotel
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Welcome to the Embassy Suites San Luis Obispo hotel. Conveniently located in the heart of California's breathtaking central coast, we are just off Highway


	San Luis Obispo San Luis Inn and Suites				From $39.95/nt
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At San Luis Inn and Suites we want you to enjoy our clean, comfortable, pleasantly decorated rooms making this your vacation home. Feel free to enjoy our


	Rodeway Inn San Luis Obispo				From $51.99/nt 1 Star Hotel
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"The rodeway inn is very conveniently located at the 101 south santa rosa exit. This san luis obispo hotel is close to cal poly, cuesta college, pismo


	Los Padres Inn San Luis Obispo				From $69.00/nt
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Inn/Chalet Additional Property Description - This Charming Hotel Is Located Near The Heart Of Downtown Sun Luis Obispo Only Five Blocks Away From Shopping


	Americas Best Value Inn San Luis Obispo				From $52.00/nt 2 Star Hotel
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Welcome to the Americas Best Value Inn of San Luis Obispo, CA. We are conveniently located half a mile from Cal Poly University, downtown, county government


	La Cuesta Inn				From $109.00/nt 3 Star Hotel
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Welcome to a place of comfort and convenience. La Cuesta Inn is the perfect hotel for both leisure and business travelers. La Cuesta Inn is conveniently

Hotels in the Los Osos/Morro Bay area. (5 miles away)

	La Serena Inn Morro Bay				From $74.00/nt 2 Star Hotel
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La Serena Inn located Morro Bay has a very relaxed pace and boasts many fine restaurants, shops and art galleries. Choose a challenging 18-hole golf course


	Embarcadero Inn				From $106.67/nt 3 Star Hotel
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The Embarcadero Inn invites you to stay on the working waterfront of Morro Bay, one of the few remaining fishing villages in California. Enjoy bayside


	El Morro Masterpiece Motel Morro Bay				From $76.00/nt 2 Star Hotel
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El Morro Masterpiece Motel - all the amenities of a four-star hotel at a fraction of the price. Prints by Master Painters from Renaissance to the Moderns


	Econo Lodge South				From $26.81/nt 2 Star Hotel
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Econo Lodge South is a mile from the Museum of Natural History and Morro Bay State Park and approximately 20 miles from San Luis Obispo County Regional


	Breakers Motel Morro Bay				From $48.00/nt 2 Star Hotel
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Just a short walk to local beaches, the Breakers Motel is only minutes to Morro Bay Aquarium, Morro Bay State park, museums, shopping, swimming, restaurants


	Anchor Inn				From $129.00/nt 2 Star Hotel
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The Anchor Inn is conveniently located one block away from the waterfront and popular restaurants, shops and art galleries. Area wineries and Hearst Castle


	Sea Air Inn Morro Bay				From $79.99/nt 2 Star Hotel
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Sea Air Inn Morro Bay is a Magnuson Hotels affiliate conveniently located within walking distance of Morro Beach and approximately 18 miles from the San


	Travelodge Morro Bay Sunset				From $39.20/nt 2 Star Hotel
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This hotel is located 20 miles from San Luis Obispo County Regional Airport and is one block from the waterfront shops and restaurants.

We have over 200 properties in the Los Osos, California area.
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Los Osos Vacation Rentals | Hotels