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Cape Girardeau Vacation Rentals and Hotels

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We have over 60 properties in the Cape Girardeau, Missouri area.
Please browse our top 30 properties below
Vacation Rentals in the Cape Girardeau/Black area. (77 miles away)
Secluded Cottage in Black MO #186 From $125/night, $775/week
3 Beds 2 Baths Sleeps 10 Cottage 3 photos Real-Time Calendar
Koinania Cottage is the place where you can leave behind your concrete, traffic and pollution, your busy schedules, stresses, worries and cares and just relax and find peace in these beautiful scenic surroundings. Outside your door there is a gently flowing creek. Cows and horses graze in the nearby ...
 
Hotels in the Cape Girardeau area.
 
Holiday Inn Express Suites Cape Girardeau From $98.60/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
Welcome to the Holiday Inn Express Hotel & Suites Cape Girardeau. The hotel was built in 2005 and offers free Express Start Breakfast with daily hot items.
 
Holiday Inn Express Suites Cape Girardeau From $98.60/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
Welcome to the Holiday Inn Express Hotel & Suites Cape Girardeau. The hotel was built in 2005 and offers free Express Start Breakfast with daily hot items.
 
Drury Lodge Cape Girardeau From $74.99/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
NOW SERVING FREE HOT QUICKSTART BREAKFAST. ENJOY SCRAMBLED EGGS/SAUSAGE/BELGIAN WAFFLES/BISCUITS AND GRAVY AND MUCH MORE. ALSO FREE HIGH-SPEED INTERNET
 
Victorian Inn and Suites From $73.95/nt  
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Free breakfast with over 25 items, indoor heated pool, large whirlpool, free high speed wireless internet in every room, located right off of I-55, microwaves
 
Cape Girardeau Hampton Inn Cape Giradeau From $113.40/nt   A 2 Star Hotel! 2 Star Hotel
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The Hampton Inn Cape Girardeau hotel is located off Interstate 55 four miles west of downtown Cape Girardeau Missouri. Area attractions near our hotel
 
Pear Tree Inn Cape Girardeau From $76.99/nt   A 2 Star Hotel! 2 Star Hotel
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ENJOY A VISIT TO CAPE GIRARDEAU. LOCATED IN AN EASILY ACCESSIBLE AREA AT A MAJOR I-55 EXIT AND WITHIN BLOCKS OF SHOPPING/HEALTH CARE FACILITIES AND SOUTHEAST
 
Drury Suites Cape Girardeau From $109.99/nt   A 3 Star Hotel! 3 Star Hotel
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The Drury Suites is the place to stay. Check into your room and relax in a spacious two-room suite. All suites have separate bedroom and living areas for
Hotels in the Cape Girardeau/Jackson area. (5 miles away)
 
Drury Inn & Suites Jackson From $89.99/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
NOW SERVING FREE HOT QUIKSTART BREAKFAST. ENJOY SCRAMBLED EGGS/SAUSAGE BELGIAN WAFFLES/BISCUITS AND GRAVY AND MUCH MORE. ALSO FREE HIGH-SPEED INTERNET
Hotels in the Cape Girardeau/Sikeston area. (29 miles away)
 
Super 8 Sikeston Miner Area From $54.99/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
Welcome to the Super 8 in Sikeston, Missouri. * Convenient location off of Interstate 55 between Memphis and St. Louis. * FREE WIRELESS HIGH SPEED INTERNET
 
Days Inn Sikeston From $50.97/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
This hotel features complimentary continental breakfast, free expanded cable with HBO, ESPN and ESPN2, fresh baked cookies after 4 pm, and fresh coffee.
 
Holiday Inn Express Sikeston Mo From $90.00/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
The Holiday Inn Express Sikeston hotel is located at Mile Marker 67, off Interstate 55. Our hotel features free high-speed Internet, free local phone calls,
 
Sikeston Comfort Inn and Suites From $89.99/nt   A 2 Star Hotel! 2 Star Hotel
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Interstate location between Memphis and St. Louis in commercial area. One half mile from famous Lambert's Cafe (home of throwed rolls).
 
Country Hearth Sikeston From $55.99/nt   A 1 Star Hotel! 1 Star Hotel
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Country Hearth Inn Offers Free Local Phone Calls, Hot Tub Suites With Microwave And Refrigerator, Dataports, The *Inn*Credible Breakfast And Home Baked
 
Pear Tree Inn Sikeston From $52.99/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
Enjoy a visit to Sikeston! Stay with Drury and experience Lambert's Cafe Home of the Throwed Rolls, the Sikeston Bootheel Rodeo and the Charleston Azalea
 
Sikeston Best Western Coach House Inn From $84.95/nt   A 2 Star Hotel! 2 Star Hotel
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The Best Western Coach House Inn has 58 spacious suites, including standard, deluxe and executive suites. All rooms feature air conditioning and heat
 
Drury Inn Sikeston From $79.99/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
NOW SERVING FREE HOT QUIKSTART BREAKFAST. ENJOY SCRAMBLED EGGS/SAUSAGE/BELGIAN WAFFLES/BISCUITS AND GRAVY AND MUCH MORE. ALSO FREE HIGH-SPEED INTERNET
Hotels in the Cape Girardeau/Charleston area. (31 miles away)
 
Econo Lodge Charleston From $64.99/nt   A 1 Star Hotel! 1 Star Hotel
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Free High Speed Internet, Free Hot Breakfast. Easy access to I-57, I-55, US60 and US62. Free use of local health club. Outdoor seasonal pool and HBO/Cable.
 
Comfort Inn Charleston From $99.99/nt   A 2 Star Hotel! 2 Star Hotel
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Easy access to I-57 & I-55. FREE use of nearby health club. FREE high speed Internet access in all rooms, lobby, and breakfast area. The hotel offers a
Hotels in the Cape Girardeau/Perryville area. (31 miles away)
 
Super 8 Perryville Mo From $61.20/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
Welcome to the Super 8 located in Perryville, MO Our property is located at a convenient location on Interstate 55, Exit 129 between St. Louis and Memphis
 
Perryville Americas Best Value Inn From $61.99/nt   A 2 Star Hotel! 2 Star Hotel
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Welcome to Americas Best Value Inn of Perryville, MO. We are located on Interstate I-55 Exit 129. Our hotel is within walking distance of the Movie Gallery
 
Comfort Inn Perryville From $72.99/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
Well appointed decor. Close to shops and restaurants. Meeting space is available On route to St. Louis and Memphis. Free long distance to anywhere in the
Hotels in the Cape Girardeau/Dexter area. (40 miles away)
 
Americas Best Value Inn From $54.95/nt   A 1 Star Hotel! 1 Star Hotel
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Welcome to the Americas Best Value Inn Dexter, conveniently located close to attractions like the Historical Stars and Stripes Museum and many dining options.
 
Country Hearth Dexter From $58.59/nt   A 1 Star Hotel! 1 Star Hotel
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The Dexter Country Hearth Inn is everyone*s home away from home. We offer free local calls, Inn-Credible breakfast, and hot tub suites. Local restaurants
 
Oak Tree Inn Dexter From $61.99/nt  
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With extra-quiet guest rooms and light-proof draperies, the Oak Tree Inn is Dexters newest hotel. This 100-percent non-smoking property offers comfortable
Hotels in the Cape Girardeau/Sainte Genevieve area. (52 miles away)
 
Microtel Inn & Suites Sainte Genevieve From $55.97/nt   A 2 Star Hotel! 2 Star Hotel
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Microtel Inn and Suites Ste. Genevieve, MO - Enjoy a Quality Hotel Room at a Discount Hotel Price. Enjoy consistency, quality, reasonable prices and great
Hotels in the Cape Girardeau/Farmington area. (54 miles away)
 
Days Inn Farmington From $44.20/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
Newly renovated * Quiet surroundings * Large, comfortable rooms * Free Continental Breakfast 6 AM - 10 AM including Asstd Bagel, asstd cereal, donuts,
 
Super 8 Farmington Mo From $56.95/nt   A 2 Star Hotel! 2 Star Hotel
Overview | Map | Hotel
Centrally located in the Maple Valley Shopping Center Several dining and shopping locations within walking distance Free Wireless High Speed Internet in
 
Holiday Inn Express Hotel & Suites Farmington From $93.95/nt   A 3 Star Hotel! 3 Star Hotel
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Welcome to the Holiday Inn Express Hotel & Suites Farmington located in the heart of the Maple Valley shopping center, at the intersection of Hwy 67 &
 
Lodge at Eagle Lake Farmington From $89.00/nt   A 3 Star Hotel! 3 Star Hotel
Overview | Map | Hotel
This is a real golf, wine and antique connoisseurs dream come true. The Lodge is away from it all to really enjoy an exclusive vacation get-a-way. Premium
We have over 60 properties in the Cape Girardeau, Missouri area.
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